Research/Technical Citations relevant to HCM in Cats

• "Utility of measuring plasma N-terminal pro-brain natriuretic peptide in detecting hypertrophic cardiomyopathy and differentiating grades of severity in cats," G. Wess, P. Daisenberger, M. Mahling, J. Hirschberger, K. Hartmann, Veterinary Clinical Pathology, vol. 40, no. 2, pp. 237-244, 2011. abstract
• "The Effect of Atenolol on NT-proBNP and Troponin in Asymptomatic Cats with Severe Left Ventricular Hypertrophy because of Hypertrophic Cardiomyopathy: A Pilot Study," S.W. Jung SW, M.D. Kittleson, Journal of Veterinary Internal Medicine, epub. 2011. abstract
• "Is treatment of feline hypertrophic cardiomyopathy based in science or faith?: A survey of cardiologists and a literature search," M. Rishniw and P.D. Pion, Journal of Feline Medicine & Surgery, vol. 13, no. 7, pp. 487-497, 2011. abstract
• "Prevalence of MYBPC3 gene mutations and association with hypertrophic cardiomyopathy in several cat breeds," M. Longeri, et al., Italian Journal of Animal Science, vol. 10, no. 1s, 2011. abstract
• "Hypertrophic cardiomyopathy in young Maine Coon cats caused by the p.A31P cMyBP-C mutation - the clinical significance of having the mutation," M. Godiksen, et al., Acta Veterinaria Scandinvica, vol. 53, no. 1, 2011. PDF
• "NT-proBNP measurement fails to reliably identify subclinical hypertrophic cardiomyopathy in Maine Coon cats," M. Singh, M. Cocchiaro, M.D. Kittleson, Journal of Feline Medicine and Surgery, vol. 12, no. 12, pp. 942-947, 2010. abstract
• "Insights into genotype-phenotype correlation in hypertrophic cardiomyopathy. Findings from 18 Spanish families with a single mutation in MYBPC3," M. Oliva-Sandoval, F. Ruiz-Espejo, L. Monserrat, M. Hermida-Prieto, M. Sabater, E. García-Molina, M. Ortiz, M. Rodríguez-García , L. Núñez, J. Gimeno, A. Castro-Beiras, M. Valdés, Heart, vol. 96, no. 24, pp. 1980-1984, 2010. abstract
• "Population characteristics and survival in 127 referred cats with hypertrophic cardiomyopathy (1997 to 2005)," J. Payne, V.L. Fuentes, A. Boswood, D. Connolly, H. Koffas, D. Brodbelt, Journal of Small Animal Practice, vol. 51, no. 10, pp. 540-547, 2010. abstract
• "The yield of risk stratification for sudden cardiac death in hypertrophic cardiomyopathy myosin-binding protein C gene mutation carriers: focus on predictive screenin," I. Christiaans, E. Birnie, I. van Langen, K. van Spaendonck-Zwarts, J. P. van Tintelen, M. van den Berg, D. Atsma, A. Helderman-van den Enden, Y. Pinto, J. Hermans-van Ast, G. Bonsel GJ, A. Wilde, European Heart Journal, vol. 31, no. 7, pp. 842-848, 2010. article
• "Re: Association of A31P and A74T polymorphisms in the myosin binding protein C3 gene and hypertrophic cardiomyopathy in Maine Coon and other breed cats," M. D. Kittleson, K. Meurs, M. Munro, Journal of Veterinary Internal Medicine, vol. 24, no. 6, pp. 1242-1244, 2010.
• "Association of A31P and A74T polymorphisms in the myosin binding protein C3 gene and hypertrophic cardiomyopathy in Maine Coon and other breed cats," G. Wess, C. Schinner, K. Weber, H. Küchenhoff, and K. Hartmann, Journal of Veterinary Internal Medicine, vol. 24, no. 3, pp. 527-532, 2010. abstract
• "Prevalence of the MYBPC3-A31P mutation in a large European feline population and association with hypertrophic cardiomyopathy in the Maine Coon breed," J. Mary, V. Chetboul, C. Sampedrano, M. Abitbol, V. Gouni, E. Trehiou-Sechi, R. Tissier, G. Queney, Jean-Louis Pouchelon, and A. Thomaset, Journal of Veterinary Cardiology, vol. 12, no. 3, pp. 155-161, 2010. abstract
• "Analysis of 8 Sarcomeric Candidate Genes for Feline Hypertrophic Cardiomyopathy Mutations in Cats with Hypertrophic Cardiomyopathy," K. M. Meurs, M. Norgard, M. Kuan, J. Haggstrom, M. Kittleson, Journal of Veterinary Internal Medicine, vol. 23, no. 4, pp. 840-843, 2009. abstract
• "Investigation into the use of plasma NT-proBNP concentration to screen for feline hypertrophic cardiomyopathy," A. Hsu, M.D. Kittleson, A. Paling, Journal of Veterinary Cardiology, vol. 11, suppl. 1, pp. S63-70, 2009. abstract
• "Expression Patterns of Cardiac Myofilament Proteins: Genomic and Protein Analysis of Surgical Myectomy Tissue From Patients With Obstructive Hypertrophic Cardiomyopathy," J. Theis, J. M. Bos, J. Theis, D. Miller, J. Dearani, H. Schaff, B. Gersh, S. Ommen, R. Moss, M. Ackerman, Circulation: Heart Failure vol. 2, no. 4, pp. 325-333, 2009. article
• "Prospective Echocardiographic and Tissue Doppler Imaging Screening of a Population of Maine Coon Cats Tested for the A31P Mutation in the Myosin-Binding Protein C Gene: A Specific Analysis of the Heterozygous Status," C. C. Sampedrano, V. Chetboul, et al., Journal of Veterinary Internal Medicine, vol. 23, pp. 91–99, 2009.
• "Prevalence of the Myosin-Binding Protein C Mutation in Maine Coon Cats," R. Fries, A. Heaney, K. M. Meurs, Journal of Veterinary Internal Medicine, vol. 22, no. 4, pp. 893-896, 2008. abstract
• "Prevalence of myocardial hypertrophy in a population of asymptomatic Swedish Maine coon cats," S. Gundler, A. Tidholm, and J. Häggström, Acta Veterinaria Scandinvica, vol. 50, no. 1, pp. 22-27, 2008. PDF
• "A substitution mutation in the myosin binding protein C gene in ragdoll hypertrophic cardiomyopathy," K. M. Meurs, M. Norgard, M. Ederer, K. Hendrix, and M. Kittleson, Genomics, vol. 90, no. 2, pp. 261-264, 2007. article
• "Pathology of End-stage Remodeling in a Family of Cats with Hypertrophic Cardiomyopathy," M. Cesta, C. Baty, B. Keene, I. Smoak, D. Malarkey, Veterinary Pathology, vol. 42, pp. 458–467, 2005.
• "A cardiac myosin binding protein C mutation in the Maine Coon cat with familial hypertrophic cardiomyopathy," K. Meurs, X. Sanchez, R. David, N. Bowles, J. Towbin, P. Reiser, J. Kittleson, M. Munro, K. Dryburgh, K. MacDonald, M. Kittleson, Human Molecular Genetics, vol. 14, no. 23, pp. 3587–3593, 2005.
• "Feline idiopathic cardiomyopathy: a retrospective study of 106 cats (1994-2001)," Ferasin L, Sturgess CP, Cannon MJ, Caney SM, Gruffydd-Jones TJ, Wotton PR.
• "Hypertrophic cardiomyopathy in two kittens," Y. Fujii, et al. Journal of Veterinary Medical Science, vol. 63, no. 5, pp. 583-585, 2001. abstract
• "Familial Hypertrophic Cardiomyopathy in Maine Coon Cats: An Animal Model of Human Disease," M. Kittleson, K. Meurs, M. Munro, J. Kittleson, Si-Kwang Liu, P. Pion, J. Towbin, Circulation, vol. 99, pp. 3172-3180, 1999.